Dr. Karen Herbst is propably the most familiar medical doctors on earth ATM when it comes to adipose tissue (fat tissue) and the abnormalities.
There are two (1
) recently (Feb 2012) published studies available in Pubmed by Dr. Karen Herbst. Both talk about the fact that in RADs (Rare Adipose Disorder) the accumulation of fat is not simply because of obesity but that the origin is different.
E.g. in Dercum's disease one may have accumulations of fat which could be confused with normal obesity gained by lifestyle selections.
She also wants to highlight that sometimes RADs masquerade as obesity and she states:
Although lifestyle changes and bariatric surgery work effectively for the obesity component of RADs, these treatments do not routinely reduce the abnormal subcutaneous adipose tissue (SAT) of RADs. RAD SAT likely results from the growth of a brown stem cell population with secondary lymphatic dysfunction in MSL, or by primary vascular and lymphatic dysfunction in lipedema and DD. People with RADs do not lose SAT from caloric limitation and increased energy expenditure alone.
Ok, that's pretty self-evident for the most of us but it's good to have it now in Pubmed too.
She proposes somekind of diagnostic criteria, histology and pathophysiology for RADs to separate them from normal obesity.
Her treatments include lymphatic decongestive therapy, medications and supplements that support loss of RAD SAT (abnormal fat).
The basis of lymphatic decongestive therapy is that when the lymphatic system is blocked, infection-fighting material is prevented from destroying toxins and germs. Cell-nourishing material is prevented from reaching the blood stream. The end result is that germs grow, our blood loses needed protein, and infectious diseases could potentially affect you.
The lymphatic system is primarily responsible for carrying disease-fighting material to cells attacked by germs, transporting the dead germs away and supplying protein-rich plasma fluid back to the heart. When this system is blocked, we become defenseless against attacks by virus, fungi, and bacteria.