...when a new and deadly lung disease broke out among legionnaires in Philadelphia in July 1976, two hundred twenty-two people became ill and thirty-four died. The cause of the lung disease remained a medical mystery for over five months. Bacterial infection was ruled out when all tests were reported as negative. Fortunately, one astute and careful microbiologist finally discovered bacteria. Joe McDade at the Leprosy Branch of the CDC, was able to detect “unusual bacteria” in guinea pigs experimentally infected with lung tissue from the dead legionnaires. Further modification of bacterial culture methods finally allowed the isolation of causative bacteria, now known as Legionella pneumophila.

HI Matt:

I never studied lipomas for bacteria.....although I found bacteria in inflammations of the fatty portion of the skin (panniculitis). Also there is some evidence that similar bacteria are found in "benign" diseases.

I honestly can't answer your question, but it wouldn't surprise me if bacteria were eventually found in connection with fat tumors. (emphasis added by Matt) I also think these bacteria, which we all carry, are implicated in many forms of disease.......perhaps one's genetic makeup determines how these bacteria eventually influence the cancerous and non-cancerous diseases that plague us all eventually.

We have much to learn.

Thanks for your interest.

Dr C

Livingston V, Allen RM.
Presence of consistently recurringinvasive mycobacterial forms in tumor cells. Microscop Soc
Bull 1948;2:5–18.

Smith had long suspected a bacterial cause for human cancer and criticized pathologists for drawing:

Too sharp a demarcation between malignant tumors, on the one hand, where the cells of the animal or human host, acting under some unknown stimulus are responsible for the tumerous growth and granulomata (benign tumors) on the other hand, such as tuberculosis and actinomycosis, where a visible microbe is responsible for the primary tumor, and the direct migration of this microbe for any secondary tumors that may appear. Rogers, 1952

Smith’s conclusion:

At the bottom, I think the distinction between such a disease, for example as tuberculosis or leprosy and malignant tumors is not as sharp as some histologists have been inclined to believe. Rogers, 1952

• oncolytic viruses find their way into the supportive intracellular milieu that prevents free-flow of the produced viruses.
• the host may have reexisting antibodies to the virion capsules thus decreasing the effective dose of the inoculum
• the host has innate immunity protection against the viral infection
• the host will mount a potent cellular and antibody response to the virus infection, potentially compromising follow-up treatments
• tissue architecture may include fibrotic areas that prevent viral spread
• tumor necrosis may also prevent viral spread
• the immune response may generate tumor and normal cell death.

• Lipomas are often solitary lumps with little metabolism
• Many treatments, like phosphatidylcholine, may initially work but slowly loses it's effect and lipoma will start to grow again
• Lipomas often have fibrotic areas
• Lipomas often have necrosis

Although these forms have been observed in stained tissue histopathologic specimens for many decades, most are ignored and generally regarded as diagnostically insignificant staining artifacts or debris. It is hypothesized that these pleomorphic forms are not staining artifacts/cellular debris, but instead represent various stages in the life cycle of stressed bacteria: cell wall-deficient/defective (often called L-forms) that are difficult-to-culture or nonculturable.

Despite a voluminous literature on the subject and general non acceptance of the role of persisting forms (bacteria?) in cancerous tissues, the time may now be propitious to mobilize and utilize modern molecular microbiological technology to define the nature of pleomorphic bodies in a variety of cancers.

dannyg wrote:Just noticed one of the Ayurvedic medicines (that worked on someone on this forum) called Gulguluthikthakam - fights bacteria! Here's the full description: "Various types of bacterial and fungal infections, eczema, candidacies, psoriasis, allergic dermatitis, sinusitis."

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