Have you ever considered what is lipoma really about? I have a hard time believing that lipomas are just a genetic disorder in us. I currently feel that something triggers the genes to start producing excessive amounts of fat cells. I have a hypothesis why this happens and I've written something about it in the What Causes Lipomas thread.



Basically, I see there is only one reason for the lipoma growth. There must be some triggering effect to it. And I believe the trigger is external or environmental. It makes no sense that the body - being developed by the evolution for ages - would create unharmful lumps without any reason.

Evolution has a habit of eliminating all features not useful tu us, like our tails. I mean we all still have our tailbone but it has been drastically diminished. Some long time ago our ancestors had a tail but because modern human no longer needs it, it has almost vanished.

In the same way, I believe, all tumors would have vanished a long time ago IF they weren't somehow beneficial to us.

So what is lipoma then?

Dr. Simoncini believes that lipoma is like a cyst caused by fungi. He believes fungal infection generates a chain reaction to which the body responds by surrounding the fungal cells with fat tissue. I have since reading that expanded my view that it is not necessarily fungi that causes the inflammation but perhaps a pleomorphic bacteria meaning that either all microorganisms share ability to resemble each other or that some bacteria are capable of transforming into looking like virus, bacteria or fungi.

There are numerous other hints which point to the bacterial causation too. Many so-called carcinogenics (e.g. radiation, agent orange or dioxin, tobacco, asbestos, red meat, immune system-suppressing drugs, heavy metals) are praised by bacteria and fungi.

Sometimes even MD's can misdiagnose cyst as a lipoma - and vice versa. But cyst consists of inflammated fluids, or semi-solid material where lipoma consists of fat cells. Cyst is often located right below the skin and may be pretty easily bursted (something you can't do with a lipoma).

Here's a short video describing a cyst:


What Causes Lipomatosis?

I believe lipomatosis happens because somehow the microorganisms or the infected cells escape from the lump. We have discussed about this lipoma multiplying effect before. I do not believe there's any predisposition or dislocation in our genes when we born except if the translocation has been inherited by either one of our parents. In that case the mutation caused by the microorganism has somehow been spread to the sex cells.

While this is all just speculation, there's strong evidence that properties gathered during our lifetime can and do pass on to our children. This is called epigenetics. It means that non-genetic factors (i.e. bacteria) can cause the organism's genes to behave (or "express themselves") differently. The DNA you pass on to your children could already be more prone to develop lipomas because you were infected. In epigenetics there are not necessarily mutations but a certain "cell memory". This could pretty much explain why some consider lipomas are inherited.

Still, even if inherited, I don't think that lipomas would start appearing without a reason. Maybe some of us have inherited genes which are already in a high-alert mode and even if there's no need for the body to start surrounding the inflammation area with fat cells, it does so.

But what follows is that even if you do have an inherited translocation, you are able to change how your genes are expressed by contributing to eliminating the cause of the inflammation and thus shutting down the genes generating the lumps.

So what do you think about it? Atleast there are many arrows pointing to this direction...

Good points here! Especially about growth. Even if they were genetic, what would determine growth rates and sizes? They are growing, thats a FACT. But why? My fathers doctor compared lipomas to freckles ( hereditary features). Ok, if my freckles start growing and multiplying, I think that would be a problem. I also think that lipoma location is important. People have had them on their face- Why dont I? Why are forearms and thighs common places?

Lipoma is really a harmless group that is non-cancerous 1. This develops in the body fat tissue which are existing in your body. The actual lipoma could be remaining without treatment in the event that this not really leading to. However in situation any kind of discomfort pain or even tenderness has experience after that it's surgically eliminated as well as deliver with regard to biopsy.

johnsonbeer0099 wrote:Lipoma is really a harmless group that is non-cancerous 1. This develops in the body fat tissue which are existing in your body. The actual lipoma could be remaining without treatment in the event that this not really leading to. However in situation any kind of discomfort pain or even tenderness has experience after that it's surgically eliminated as well as deliver with regard to biopsy.

Lipomas are harmless - until they cause pain, till they wrap around a nerve, or invade an organ.

There is one post in the forum of a person who has a lipoma wrapped around his spine and is partially paralyzed as a result.

Myself, I am super careful because if I get on my knees to scrub the floor I will get new lipomas on my knees.
If I bump into something, I'll get a new lipoma on my arm or leg.

Lipomas grow, wrap around nerves, stretch the skin.

Lipomas are every bit if not MORE troublesom than teen age acne or erectile disfunction but we are told to suck it up, these are "harmless" lumps of fat.

NO. They are much more than lumps of fat. They are encapsulated, they can wrap around nerves, they grow. They disfigure.

If lipomas could get as much attention as acne, we'd have a cure.

There are even pleomorphic lipomas which are commonly confused with liposarcomas.

This shows even more that the differences between lipoma diseases and forms are not very clear. The study above suggests that atleast some of the occations where a lipoma is thought to develop into a malignant liposarcoma from benign lipoma, is because the pleomorphic lipoma is misdiagnosed.

How clear is the separation between benign versus malignant then if it is so easy to confuse the two? This emphasizes my point of view that they are not so distinct and may aswell share the same origin.

Hi,
Lipoma is a kind of disses or treatment of human body. Abdominal Pain, Hemorrhage, Obstruction and Dyspepsia represent the most common symptoms associated with gastric lipomas, Although the vast majority are thought to be symptomatic and are discovered incidentally. Lipomas closest to the pylorus can cause obstructive symptoms, frequently by obstructing the pylorus or prolapsing through the pylorus in to the duodenum.

Hi Matt,

thanks for your coment, but don't be worry about me. I have made the exercises several times because the difference between me and other is, that I have spent a long time to read everthing from the history of the researcher Prof. Dercum, other related or assumed articles from a lot of high qualified people and I had a luck to be part when the pathology made investigations into my lipomas. If I read here on my forum and others, 99 % of them carry lipoma-tumors which indicates the high mumber about most like the size of a peanut, these are totally different to mine. Firstly of the seizure and that I have relatively less. all together may be 45, but the good thing is, taht since 2 years I could not find new once.

You wrote in anothe thread you have doubt of the investgation in Pathology. I can ensure you, as far I can see, the most and the gighest interest all such examnnations is to find out is there any kind of cancer or not. I have no information that one report ring up the alarm bell!! Some pathologists are going further and loking into the structure of the lipoma to classify them from this. So far, I found out that there are different results and that is of interest. I have asked my members to send me this information for study.

Re

Klaus

Klaus,

I'm not sure if there is any connection between cancer tumors and benign tumors but I definitely cannot say there is not. Since you have studied some I would like to ask some questions:

1) Do you know what are Russell bodies (aka Mott bodies)? If not here's some information about cancer and Russell bodies.
2) Do you know if Russell bodies are found in lipoma cells?
3) Do you know if anyone has ever found microbes from lipomas?
4) Do you know how cancer is started?
5) Do you know how lipoma is started?
6) Do you know which magnification a pathologist normally uses when examining a lipoma tissue sample?
7) Have you considered that perhaps the pathologists do not know what to look for?
8) Do you know which kind of staining do they use to study the lipoma samples?

My guess is the pathologists use the HE, gram staining or something else than acid fast staining. They also propably do not magnify the sample by 1000x. In addition they are not expecting to find any bacteria from either cancer cells nor lipoma cells. It is very difficult to find anything if you are not really searching.

Dr. Cantwell also recommends using oil in the stain glass to get the Russell bodies (bacteria) visible.

Orthodoxy, however, has a dogma that says microbes always have the same form and cannot change from viruses into bacteria and fungi. This is because orthodox microbiologists commonly observe dead, stained microbes in dead tissue or live ones for short periods, instead of live microbes in live tissue at high magnification over long periods.

Thanks!

Lipomas are known to have enlarged vacuoles in the fat cells. Lipoma cells often look like one large vacuole *. Vacuoles are cell organelles and exist in most plant, bacteria, fungi and animal cells.

It should be noted that vacuoles are equivalent of the animal lysosomes *.

It is considered that vacuoles have a smaller prominence in animal cells and are thus smaller and perform mostly subordinate roles. Some of the functions of vacuoles include:

• Isolating materials that might be harmful or a threat to the cell
• Containing waste products
• Maintaining an acidic internal pH
• Containing small molecules
• Exporting unwanted substances from the cell

Thomas Boller and others proposed that the vacuole participates in the destruction of invading bacteria by surrounding and removing them from the cell. Robert B Mellor has suggested that vacuoles could be organelles shared by microorganisms and the cell. This is called as endosymbiosis; any organism that lives within the body or cells of another organism.

Mellor has reasoned this stems because the organelle that microorganisms inhabit partially takes over the lysosomal functions in these cells.

It is generally agreed that mitochondrias are originally bacteria which have now live in symbiosis with cells.

Histologically, lipomas are composed of mature fat cells showing only slight variations in size and shape. Nuclei are fairly uniform. Intranuclear vacuoles are commonly found and should not be regarded as evidence for lipoblastic activity. *

Atleast salmonella bacteria are known to survive inside the vacuole in animals. Vacuoles are acidic environments and thus proper living surroundings for bacteria.

So why are the vacuoles enlarged in lipoma cells?

This is my own speculation but I find it quite interesting that vacuoles are generally larger in fungi and bacteria than normally in animal cells. And that in lipoma cells the vacuoles seem much larger than usually.

What if the vacuoles are enlarged in lipomas because they hold bacteria inside them? Or if not bacteria directly then maybe some byproducts from the fungal or bacterial organisms? And what if these microorganisms aren't dead but actually living in symbiosis with the cell and directing it's functioning by affecting to it's DNA somehow?

But this symbiosis isn't perfect since we get benign tumors. While the microorganism flourishes we develop lumps. When the microorganisms get less food the lumps shrink. Also when antimicrobial substances are consumed the lumps seem to sometimes shrink, although lipoma cells are hardly bioavailable to external nutrients.

Here's another thread (more recent) from a forum member about the same subject:What 'Exactly' Is a Lipoma