The Guide to Find Your Cure to your lipomas

[MarkX3]

Hello,

I am compiling a guide that may help others in determining which treatment option has a good chance of working.

There is inherent danger in trying treatments. Lipomas can and will learn, it has similar mechanical properties to cancer. Chemo eventually will not work on Cancer and we do see that today. So do these lipomas, especially in people with DD, can and will develop resistance, hence lipomas produce cytokines. So you see, trying things just because can be dangerous for some. Hence this guide.

ChemoFit test is a good test to begin with. Look it up for more info. In brief, a sample of the tumour is sent to a lab and exposed to different agents to see which one works. It is not cheap. You are looking at $2000 to start with. However, I can provide you a list of things to try first, and I will post it here, once the guide is complete.

Genetic Testing, expensive at this stage, but I am finding the prices keep falling. Aside from the ATA group, there are four other interesting genes. I will not cover much on this, as most will not venture out and do any testing, however if you are interested, email me.

Liver, Kideny and other organ testing. CT scans help in finding out about lipomas, they are often and mostly misdiagnosed. As was the case with me. People with DD should talk to their doctor about CT scan of liver, etc. If you need a case to show your doctor first, email me, I can send you my particulars or just do a search on PubMed.

Finally, if you have had any testing done, ct, etc, I would be more then curious to find out about them, how you did them, how it was derived, and so forth. It would help.

Parasite testing, etc should be a must.

Finally, where I live, the doctors I try to work with are good doctors, PhD's, Emeritus, etc. It is their opinion that DD is part of, or a derivative of a mitrocondrial disease. I agree with them so far. It can be passed on only by a mother. This so far confirms the many cases on PubMed.

I'v begun a new treatment based on a chemofit test. My first injection was yesterday. Treatment is an experimental one, it will last about a month. Two injections per week along with some other things. After my first injection I slept for 6 hour straight.
I can't tell if I am just excited or the treatment is working, but my lipomas feel different, they feel softer, especially on the hand where the injection occurred. The injections are based on DCA, (google it). DCA along with few other things was injected yesterday into the blood stream. It is the combination that may work, DCA on its own will more then likely not work. I'll keep you posted, the doctor I'm working with is in Toronto, amazing doctor.

What may work for me, may not work for you. Just like cancer, some things will work for some, and not others. Please keep this in mind at all times.

Caution:

I would be extremely skeptical about any treatment for lipomas that last more then 6 months. It carries so many dangers, from developing resistance to drugs to so many other things. There are documented cases of lipoma developing resistance, as this was the case with direct lipoma injections.


So please, post what worked, and what did not worked, and especially the mechanism that have led you to try.

Again if you are going to try anything, seek a professional opinion and work with a doctor that can monitor your progress.

Thanks!

[MarkX3]

Matt, I can't upload PDFs?

[251152]

It can be passed on only by a mother. This so far confirms the many cases on PubMed.

I'm not sure about this since my mother doesn't have any lipomas while my father has 2-3 and no new ones are developing (so my condition is much worse). Also, I've seen some other people here saying that they have this condition from their fathers.

Also, could you use less abbreviations like DD, CT, DCA in your first post? I mean once you say what they are then it's ok but I personally don't know what you mean by any of those : \

What substance are you injecting yourself with and who came up with this potential solution?

[MarkX3]

With FML or Multiple lipoma the High Mobility genes can be passed down from the father (specifically HMGA2 and/or 1 Genes). However for DD (Dercum's disease) the suspect is a mitrocondrial disease.

My injections are doctor supervised, and I wouldn't venture as to do such treatments on my own. It is risky and there are neurological side effects (100% reversible), and there is a possibility of death due to TLS(That's where too many cancerous cells die off at the same time). Testing, blood, urine, heart and so on are I think necessary weekly tests, and as such I did my first round of tests.
DCA = Dichloroacetic acid.
CT = Cat Scan

I derived at DCA + few other things based on ChemoFit test. This is where a lipoma is removed, sent to a lab, and exposed to bunch of possible agents. It is also called in vivo testing. The doctor I am working with is excellent. His first recommendation was to try DCA + Chemo Therapy based on the results,... However, I choose the second best option based on the results with more then 90% shattered cells!. I'm saving chemo for last. In vivo testing does not guarantee the outcome.

Some background info, so you see, multiple lipomas can be passed down from the father, but I have yet to see any Dercum's disease being passed down by the father. HMGA2 is located 12q15, Chromosome 12
For info on how this happens, you can start with this: http://www.ucl.ac.uk/tcga/ScienceSpectr ... 14-98.html
oh and yeah, the key word here is mesenchymal

Hence, people with DD should be extremely careful with what they try. FML or MFL I suggest you do your research as cytokines are involved there too...

Note=A chromosomal aberration involving HMGA2 is associated with a subclass of benign mesenchymal tumors known as lipomas. Translocation t(3;12)(q27-q28;q13-q15) with LPP is shown in lipomas. HMGA2 is also fused with a number of other genes in lipomas.

Note=A chromosomal aberration involving HMGA2 is associated with pulmonary chondroid hamartomas. Translocation t(3;12)(q27-q28;q14-q15) with LPP is detected in pulmonary chondroid hamartomas.

Note=A chromosomal aberration involving HMGA2 is associated with parosteal lipomas. Translocation t(3;12)(q28;q14) with LPP is also shown in one parosteal lipoma.

Note=A chromosomal aberration involving HMGA2 is found in uterine leiomyoma. Translocation t(12;14)(q15;q23-24) with RAD51B. Chromosomal rearrangements involving HMGA2 do not seem to be the principle pathobiological mechanism in uterine leiomyoma.

[251152]

I see, so your condition is DD. My case is not Dercum's, cause they don't really hurt and as I mentioned my dad has them, so I guess there are different approaches to that. Thanks for the informative response and good luck with your treatment, please keep us posted.

[ryan]

My father (and mother for that matter) doesn't have any lipomas, but I have tons!

[fb88]

same here... none of my family have lipomas. Maybe I am secretly adopted.

[matt]

My parents don't have lipomas. And none of my relatives that I know of. But I think we are still the minority. Most with multiple lipomas tend to have relatives with lipomas.

[MarkX3]

I look at it this way, IBM has devised a microscope last year which can "look" and distinguish individual bond links between atoms(http://www.sciencedaily.com/releases/20 ... 074526.htm), but the cure for cancer is still going strong. We are ether all duped, or the human body(life in general) is the most sophisticated peace of living machinery we have seen so far. I may be going on a limb here, but I would say that with the current research some people are better of with fighting cancer then lipomas which have begun invading organs.

I'm off to my second experimental treatment tomorrow. Even tho the invivo testing looks good, nothing is certain, and I am taking a huge risk undergoing this treatment. It is still a calculated risk, better then taking some supplements or seeing a quack doctor, again.

[MarkX3]

FYI, I am waiting to see a researcher, a very good one, and I hope I can put some pressure on him for genetic testing to definitely answer and scientifically prove or disprove DD theory about a mitrocondrial disease. This thing has already cost me so much, and so much $$$ which goes like water, and so on. I'm tired of dealing with this disease for so long, I need these things out of my body, mind and soul.

[251152]

we all do man. What wouldn't every single member of this forum give just to get rid of this moth#(*&king curse!

[sdsurfer]

I just wanted to thank MarkX3 for sharing the knowledge that can only come from extensive research. I too have spent thousands of dollars and countless hours of research to no avail, but it is my hope that we can build off one another's knowledge to become more informed. Best of luck in your treatment

[MarkX3]

sdsurfer, I'd be more interested in what research you embarked on, and what worked and didn't work would ultimately help. Perhaps you can share your experience ? email, this board, phone call?

Your extensive research will help, even if you failed, it is one area of research that doesn't have to be repeated by someone else. This is where the power of internet collaboration will yield results.

I'm going for treatments twice a week now. There are some minor neurological side effects, and from what I read so far everything is reversible.

Thanks

[Chris]

This is very informative for me. Thanks to all. New to the group and would add that I also have multiple lipomas with none known in my immediate and extended family members.

[251152]

so MarkX3 you're doing a direct injection in the lipoma right? When will it supposedly show any results?

[MarkX3]

No, its not a direct injection into a lipoma. And the answer is, I don't know.
This is experimental, experiments under supervision are best. Things I wouldn't think of, or miss, someone else might pick it up.

I hope this will lead to something, as my for next experimental treatment: So far, I have not found a doctor crazy enough to give it a thought. And I won't venture out on risky behavior without supervision...

If DCA works in some fashion, then it will be the most efficient method to remove lipomas, hence why I think it has a good chance of working.

And it really boils down to hard $$$....

[Joe]

hi,

I came across this forum while searching for info regarding the cause of Lipoma.

Having read through many internet sites and forums my conclusion is that there is no known 'cure' or known 'cause'.

I developed my first Lipoma at 43 years old on my abdomen and this was quickly followed by 3 more. I ignored them at first until it became unconfortable when sleeping (on my front).

My solution was to have them removed. I was quite suprised to see how large they actualy were when cut out. Since that time (I am now 47 years old, and male) I have developed 3 more on my abdomen and chose to get these removed as quickly as possible. I am fortunate that I visit Asia often on business and have access to affordable surgery (in Thailand usualy).

I do not suffer from stress. I am not overweight. My parents had no Lipoma (that I was aware of). I have a healthy diet for many years and do not drink to excess.

I have started to take vitamin supplements and more regular (non impact) excercise such as cycling.

The conclusion I have come to is that one should do all that is possible to maintain a healthy lifestyle as this certainly won't do any harm, even if it does not prevent Lipoma.

I hope that these lumps will stop developing on my abdomen as suddenly as they they first started.

Until then, a healthy diet and regular non-impact excercise are generaly well adviced.

Surgery seems to be the only effective treatment.

[MarkX3]

Hi Joe,

Before you do another surgery please consider this. I have had alot removed, and thinking back I should not have done any surgeries. While doctors claim that the tumors are benign in nature, that is just a part of the incomplete truth. In a nutshell, I believe that surgeries made my condition worse. Even tho the surgeon did awesome job on each and every lipoma (pays to get a good guy), and I can not fault him. I simply would not consider another surgery unless the situation warrants it.

From researching and having read a little bit, I am more (my opinion) then certain that these lipomas may appear benign in nature, but are similar in reproduction cycle to cancer.
Yes, its a bold statement, but if you cut them out, you are in my opinion making bad situation worse. Considering the small amount of tumors you have, I'd suggest that you look into injection with DC and so on, there's another thread on here which talks about it. Injections in my opinion will work better for you. And there are no scars.

The best theory so far put forward, is to disrupt the metabolic state of lipoma.

In ether case, stay away from fake cures, as we have seen a share of those. Stay away from useless supplements that have no scientific basis to work. I believe that quite a few supplements will actually make your lipomas bigger and more resilient, by accelerating maturity of the adipose tissue.

If you consider supplements, consider (BUT DO YOUR RESEARCH) these:
NAC
Carinitine
CQ10
Green Tea

The combo I find slows down the lipomas, if you do surgery, do take NAC in higher dosage, and of course make sure you talk to your doctor and tell him about NAC. NAC is a simple amino acid that binds to toxins and some cytokines. Green Tea has been shown to disrupt some mitrocondrial energy production in various tumors, and suppress fat storage while increasing metabolic rate, I'm not sure how this plays in with thyroid. Carnitine + CQ10 is supportive of Green Tea energy production disruption and is quite effective at suppressing some of the nerve pain

Also, some suggest resveretol, extract from the skin grape, but I have yet to find a clean supply. I would take resveretrol(or however you spell it) but I can't find a good supplier.

If I were you, I'd seek an injection which can dissolve the lipoma, rather then surgery.

Considering there is no lipoma history in your family, you may develop Dercum's.

oh yeah, since you get to travel (lucky) stop eating fish from the Pacific. Recently it has been found that 100% of the blue fin tuna is contaminated from Fukoshima with radiation.

"All small PBFT (n = 28; recent migrants from Japan) had 134Cs and elevated 137Cs in their white muscle tissue. [...] We used small PBFT, known to be migrants from Japan, to test whether all migrants would demonstrate a measurable radiocesium signal from Fukushima. [...] All of the small PBFT (63.1−72.3 cm SL; ageest = 1.3−1.6 years; n = 28; hereafter “small PBFT”) had measurable concentrations of 134Cs [...] Detection of 134Cs and elevated 137Cs in 100% of small, recently migrated PBFT in 2012 suggests that other species that forage near Japan have a high probability of acquiring 134Cs and 137Cs [...]"

[251152]

MarkX3 I personally am not aware of an affordable and widely available injections that actually work.. Some on this forum said they had success in a way that the lipomas "shrank a bit" but none of them actually went away

[MarkX3]

I know that very well, still I am in a corner, now I am forced to try very experimental "remedies", or these lipomas get me. Surgery is no longer an option as I see from others and myself who have alot, where surgical removal "makes" more lipomas over time,. So in a desperate attempt, I'm putting out money on tests, invitro testing, experimenting and other crazy stuff.

I look it this way, lipoma or not, I don't care what anyone else says, but these are similar in biological behavior to cancer. The methodology of growth is the major differential aspect, lipomas grow via the fat storage mechanism, hence the mutated HGMA1 and 2. But, there are more know agents that can kill cancer than a lipoma.

BUT - there must be other agents that people have not tried, hence the invitro testing is a good start. But, it boils down to $$$, a commodity of which we all have limited supplies of.

Over the last 10 years I gained knowledge in many areas. One big missing key puzzle is access to a lab, as paying for invitro testing is not a suitable option (hence the limited $$$).